Men with erectile dysfunction (ED) can use a medicine called Fildena 100. Its principal ingredient, sildenafil citrate, is a phosphodiesterase type 5 (PDE5) inhibitor. It comes in several formulations and dose levels. During sexual stimulation, sildenafil increases blood flow to the penis, which aids in achieving and sustaining an erection. The enzyme PDE5, which breaks down cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis, is inhibited by sildenafil citrate. Elevated concentrations of CGMP promote erection facilitation, enhanced blood flow, and smooth muscle relaxation.
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